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To eat or not to eat (before exercising): That is the question

Researchers from the University of Bath in the U.K. studied a group of overweight males. The volunteers walked for 60 minutes at 60 percent maximum oxygen consumption on an empty stomach and, on another occasion, two hours after consuming a high-calorie carbohydrate -rich breakfast. The research team took multiple blood samples after eating or fasting and after exercising. The researchers also collected adipose tissue samples immediately before and one hour after walking. Gene expression in the adipose tissue differed significantly in the two trials. The expression of two genes, PDK4 and HSL, increased when the men fasted and exercised and decreased when they ate before exercising. The rise in PDK4 likely indicates that stored fat was used to fuel metabolism during exercise instead of carbohydrates from the recent meal. HSL typically increases when adipose tissue uses stored energy to support increased activity, such as during exercise, explained Dylan Thompson, corresponding autho...